EVALUATION OF MUTAGENIC, GENOTOXIC AND TRANSFORMING PROPERTIES OF UKRAIN

CHŁOPKIEWICZ B., MARCZEWSKA J., EJCHART A., ANUSZEWSKA E., KOZIOROWSKA J.

Drug Institute, 30/34 Chełmska Street, 00-725 Warsaw, Poland.

Summary: Evaluation of mutagenic and genotoxic properties of Ukrain was on the basis of the Ames and micronucleus tests. Ukrain was investigated for its ability to induce morphological transformation of embryonic cells of the Syrian hamster. Under the experimental condition used in this study, Ukrain was found to be non-mutagenic and non-genotoxic, and futhermore did not induce morphological cell transformation.