SYNERGIC INFLUENCE OF UKRAIN AND PROTOPORPHYRIN AMINO ACID CONJUGATES ON HUMAN MALIGNANT CELL LINES

BRZOSKO W.J.1*, GRACZYK A.2, KONARSKI J.2, NOWICKY J.W.3

1) Roch Brzosko Memorial Centre for Natural Medicine, Willowa 8/10, 00-790 Warsaw, Poland.
2) Military University of Technology, Warsaw, Poland.
3) Ukrain Anticancer Institute, 1040 Vienna, Austria.

* Author to whom correspondence should be addressed.

Summary: Simultaneous cytotoxicity of Ukrain and protoporphyrin amino-acid derivatives was tested on four malignant cell lines and the cytotoxic effect after laser irradiation was compared with cytotoxicity of Ukrain and protoporphyrin amino-acid derivatives applied on similar cell lines separately. It was found that Ukrain and protoporphyrin amino-acid derivatives act synergistically as cytotoxic substances on the malignant cell lines.